Co-occuring SAD symtomalogy and
schizophrenia at high latitude: a pilot study
Doorack JE, Allen J, Battaglia J
ABSTRACT [full
text] [back
to issue 66(3)]
Objectives. Recent research investigates major depression with
seasonal pattern, also called seasonal affective disorder (SAD), depression
in schizophrenia and seasonality in schizophrenia, but there exits limited
research investigating SAD in schizophrenia. This study documents co-occurring
SAD symptomatology in patients with schizophrenia at high latitude.
Study Design. Clinical cross-sectional study of patients with
schizophrenia attending treatment centres in Alaska.
Method. Twenty-eight patients completed a structured interview
assessing seasonal patterns in mood, depression, negative symptoms of
schizophrenia and alcohol use.
Results. Thirty-six percent of patients with schizophrenia met
the criteria for SAD used in previous general population research on
SAD in Alaska. When a presence of major depressive episode was confirmed
using a structured clinical interview for depression in schizophrenia,
the rate was 25%. Severity of SAD symptoms was greatest among patients
with alcohol-abuse history.
Conclusions. Co-occurring SAD symptomatology was identified in
this extreme latitude sample of patients with schizophrenia. The frequency
and severity of symptomatology was greater than found in a general population
study of SAD conducted in Alaska using identical criteria. SAD may be
under-diagnosed in schizophrenia at moderate and extreme latitudes,
highlighting clinical assessment considerations, potential utility of
bright light therapy and the need for additional research.
(Int J Circumpolar Health 2007: 66(3): 248-256).
Keywords: depression with seasonal variation, seasonal affective
disorder, SAD, schizophrenia, co-occurring disorders